Father-Daughter Duo: How Unmasking Leprosy in Father Helped in Leprosy Diagnosis in the Daughter - A Case Report

In highly endemic countries like India, where tuberculosis (TB) and leprosy infection may coexist, screening the other disease before initiating treatment is important to prevent Rifampicin resistance since both diseases are treated with and sensitive to Rifampicin. Here, we report a leprosy case involving the unmasking of leprosy in a treated patient with Pulmonary TB. In this case, a high index of suspicion of Erythema Nodosum Leprosum (ENL) in a patient with no history of leprosy disease or treatment with anti-leprosy drugs was observed. He, however, had a history of taking anti-tuberculous medicine 1.5 years earlier. This case report also acknowledges the physician’s prompt referral of this patient to a dermatologist. Taking a detailed family history and screening helped us diagnose leprosy in the patient’s daughter. It also emphasises the atypical presentation of leprosy, which (although described in textbooks) is being reported here.

An Unusual Presentation Of Erythema Ab Igne And The Role Of Occupational History In Unveiling It - A Case Report

Erythema ab igne is a characteristic reticular telangiectatic and pigmented dermatosis, resulting from repeated or prolonged exposure to heat or infrared radiation insufficient to cause burns. Occupational history has played a pivotal role in dermatological diagnosis, and its importance cannot be overstated. It could lead to the provisional or final diagnosis in many instances.Over the course of time, the site and cause of erythema ab igne has evolved. From commonly being found on knees shins and palms due to tapnas (a practice in Indian villages to sit in front of fire); the disease is now observed on other sites such as on thighs and trunk after the discovery of heating pads and laptops.In thisparticular case, a 26-year-old male presented with erythematous to light brown patches on his right arm. The site of presentation was quite unusual, thus making occupational history the key to diagnosis.

Allergic Drug Reactions: How Do The Dermatologists Of Vadodara City Perceive And Contribute To Pharmacovigilance Program?

Background:The pharmacovigilanceisimperativein defining safety profile of the drug.As cutaneous Adverse Drug Reactions (ADRs) are very common, dermatologists’ contribution to pharmacovigilanceprogram of India (PvPI) is important. This study was conducted to know dermatologists’ perception about ADRs; their awareness and participation inPvPI. Material and Methods:A Prospective, cross-sectionalsurvey was conductedamongst dermatologists, approaching via Whatsappor during academic meetings. Pre-validated questionnaire including their demographic details, perception of risk of allergic reactions, awareness of PvPI and ADRs reporting was utilized. Data analysis was done with Microsoft Excel and Graph Pad prism software. Results:Out of 73 dermatologists, 44 responded the survey (Coverage rate 60%).Highest and lowest risk amongstantimicrobials for ADRswas perceived for sulphonamides and cephalosporins respectively. Amongstnon-antimicrobials, it was Non-steroidal anti-inflammatory drugs (NSAIDs) and local anaesthetics respectively. Awareness about PvPI was seen in 94% and 38% of dermatologists working in an institute and in a private set up respectively. Amongst them, 78% and 18% had ever reported ADRs to PvPI. Conclusions:Sulphonamides and NSAIDs were perceived to have higher risk ofADRs. Limited number of dermatologists have contributed to national ADR database amongst the ones who are aware of PvPI.